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The EpiDerm Full Thickness Skin tissue EFT-412 (1.0?cm 2 surface area) consists of normal, human epidermal keratinocytes and dermal fibroblasts (Fig. 3A , Lower Panel). Both types of cells are cultured to form a multilayered model of the human dermis and epidermis that are mitotically and metabolically Munith MI 24hrs cash loans active. EFT-412 skin tissue is an ideal in vitro system to study the anti-aging efficacy of cosmetic ingredients and formulations, and is applied in the following experiments.